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Poser’s criteria for the diagnosis of
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бет | 5/6 | Дата | 16.11.2023 | өлшемі | 2,26 Mb. | | #191542 |
| Байланысты: Презентация на тему Демиелинизирующие заболевания ЦНСPoser’s criteria for the diagnosis of
MS
Clinically definite MS
A1: 2 Attacks 2 lesions on examination
A2: 2 Attacks 1 lesion on examination 1 paraclinical
lesion
Laboratory-supported definite MS
B1: 2 Attacks 1 lesion on examination or 1 paraclinical
lesion abnormal CSF
B2: 1 Attack 2 lesions on examination abnormal CSF§
B3: 1 Attack 1 lesion on examination 1 paraclinical
lesion‡ abnormal CSF
Clinically probable MS
C1: 2 Attacks 1 lesion on examination
C2: 1 Attack 2 lesions on examination
C3: 1 Attack 1 lesion on examination 1 paraclinical
lesion
- Age-related white matter changes
- Acute disseminated encephalomyelitis
- Behc~et disease
- Bacterial infections (syphilis, Lyme disease)
- Cerebral autosomal dominant arteriopathy, subcortical infarcts,and leukoencephalopathy
- Cervical spondylosis or stenosis
- HIV infection
- Human T-lymphotrophic virus I/II
- Ischemic optic neuropathy (arteritic and nonarteritic)
- Leukodystrophies (e.g., adrenoleukodystrophy, metachromatic
- leukodystrophy)
Diagnostic considerations in patients with suspected MS or MRI white matter abnormalities - Neoplasms (e.g., lymphoma, glioma, meningioma)
- Migraine
- Sarcoid
- Sjo¨gren syndrome
- Stroke and ischemic cerebrovascular disease
- Systemic lupus erythematosus, antiphospholipid antibody syndromes, and related collagen vascular disorders
- Unidentified bright objects
- Vascular malformations
- Vasculitis (primary CNS or other)
- Vitamin B12 deficiency
Лечение - Этиотропной терапии нет
- Патогенетическая терапия
- Иммуносупрессия
- Глюкокортикостероиды
- Цитостатики
- Плазмаферез
- Иммуномодуляция
- Интерферон (копаксон и бетаферон)
- Симптоматическая терапия
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