Демиелинизирующие заболевания: Рассеянный склероз


Poser’s criteria for the diagnosis of



бет5/6
Дата16.11.2023
өлшемі2,26 Mb.
#191542
1   2   3   4   5   6
Байланысты:
Презентация на тему Демиелинизирующие заболевания ЦНС

Poser’s criteria for the diagnosis of
MS
Clinically definite MS
A1: 2 Attacks 2 lesions on examination
A2: 2 Attacks 1 lesion on examination 1 paraclinical
lesion
Laboratory-supported definite MS
B1: 2 Attacks 1 lesion on examination or 1 paraclinical
lesion abnormal CSF
B2: 1 Attack 2 lesions on examination abnormal CSF§
B3: 1 Attack 1 lesion on examination 1 paraclinical
lesion‡ abnormal CSF
Clinically probable MS
C1: 2 Attacks 1 lesion on examination
C2: 1 Attack 2 lesions on examination
C3: 1 Attack 1 lesion on examination 1 paraclinical
lesion

Diagnostic considerations in patients with suspected MS or MRI white matter abnormalities

  • Age-related white matter changes
  • Acute disseminated encephalomyelitis
  • Behc~et disease
  • Bacterial infections (syphilis, Lyme disease)
  • Cerebral autosomal dominant arteriopathy, subcortical infarcts,and leukoencephalopathy
  • Cervical spondylosis or stenosis
  • HIV infection
  • Human T-lymphotrophic virus I/II
  • Ischemic optic neuropathy (arteritic and nonarteritic)
  • Leukodystrophies (e.g., adrenoleukodystrophy, metachromatic
  • leukodystrophy)

Diagnostic considerations in patients with suspected MS or MRI white matter abnormalities

  • Neoplasms (e.g., lymphoma, glioma, meningioma)
  • Migraine
  • Sarcoid
  • Sjo¨gren syndrome
  • Stroke and ischemic cerebrovascular disease
  • Systemic lupus erythematosus, antiphospholipid antibody syndromes, and related collagen vascular disorders
  • Unidentified bright objects
  • Vascular malformations
  • Vasculitis (primary CNS or other)
  • Vitamin B12 deficiency

Лечение

  • Этиотропной терапии нет
  • Патогенетическая терапия
    • Иммуносупрессия
      • Глюкокортикостероиды
      • Цитостатики
      • Плазмаферез
    • Иммуномодуляция
      • Интерферон (копаксон и бетаферон)
  • Симптоматическая терапия



Достарыңызбен бөлісу:
1   2   3   4   5   6




©engime.org 2024
әкімшілігінің қараңыз

    Басты бет