19
Клиническая медицина
Медицина и экология, 2021, 3
Обзоры литературы
R. Kh. Begaidarova
1
*, D. A. Bayesheva
2
, Sh. A. Kulzhanova
2
, G. D. Zhumagaliyeva
3
, G. N. Abuova
4
, B. N. Kosherova
1
MODERN APPROACHES FOR TREATMENT AND PREVENTION OF INFLUENZA AND ARI WITH
THE USE OF INTERFERON KAGOCEL INDUCTOR
1
Medical University of Karaganda (Karaganda, Republic of Kazakhstan),
2
Medical University of Astana (Nur-Sultan, Republic of Kazakhstan),
3
West Kazakhstan Medical University named after V.I. M. Ospanova (Aktobe, Republic of Kazakhstan),
4
South Kazakhstan Medical Academy (Shymkent, Republic of Kazakhstan)
__________________________________________________________________
*Rozalia Khasanovna Begaidarova –
Doctor of Medical Sciences, Professor of the Department of Infectious Diseases
and Phthisiology, Karaganda Medical University (Karaganda, Republic of Kazakhstan); e-mail: begaydarova@qmu.kz
__________________________________________________________________
The problem of choosing an effective etiotropic therapy for influenza and ARVI has been and remains one of
the most urgent in world health care. For the treatment and prevention of respiratory viral diseases, a specific pool of
drugs, both direct and mediated by immune reactions, of antiviral action is recommended. Our literature review is de-
voted to a representative of one of the proven effective groups of antiviral drugs - interferon inducers - Kagocel.
Kagocel, as an antiviral drug, in a number of multicenter blind placebo-controlled registration and observation-
al post-registration studies has demonstrated high clinical efficacy and safety in the prevention and treatment of influ-
enza and ARVI, as well as their complications.
The results of clinical trials and post-registration observational studies also confirmed the effectiveness of Ka-
gocel in the treatment of herpes virus infection. The results of a new in vitro study showed that Kagocel is active in
suppressing the multiplication of the new SARSCoV-2 coronavirus, which undoubtedly made it one of the potential
drugs for the prevention and treatment of COVID 19.
Kagocel demonstrates a synergistic effect when combined with other antiviral and immunomodulatory drugs.
Key words:
prevention and treatment of ARI/influenza, interferon inducers, Kagocel, SARSCoV-2, COVID 19,
immunomodulators, immunotropic drugs.
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