Клиническая медицина The skin, as an organ, acts as the barrier
between the external environment and the body
[8, 10]. Various risk factors from the environment
can produce, in certain circumstances, changes in
skin structure and are associated with various
skin diseases. In the context of environmental
risk factors impacting upon the structure of the
skin, these include pollutants, temperature
changes, climatic variations, hormonal factors
and, not least, exposure to ultraviolet radiation
without adequate protection [11, 15].
Given these risk factors, there are numer-
ous external forces that can cause skin changes
[7]. As well as associated pathologies, there are
numerous studies that show how biomolecular
mechanisms and pathophysiology are connected
to changes to the skin, giving rise to dermatologi-
cal disorders [3, 14]. For these reasons, this
study looks at, in addition to polluting factors,
eating. This is a factor that can affect the func-
tionality of organs, although the effect is general-
ly viewed as tegumental [3, 5]. Similarly, changes
that occur in the skin layers, producing altera-
tions in niveliul down to six layers, cause changes
to subcomponents and ultrastructural type [1, 2].
The changes occur in the dermis and epidermis
are linked to alternations to subcomponents.
The study outlined in this paper is useful
for examining skin pathology idea, particularly
with the medical examination of children. Chil-
dren are the most commonly affected segment of
the population. After this age group, as children
become older, this condition is often followed by
a degree of disability in relation to impaired tegu-
mentuilui. Older people have a high vulnerability
to disease. Among the different dermatological
disorders that affect the skin, melanocytic nevi
are considered the most common pathology [14].
In context, melanocytic nevi can be found at an
early age, those from childhood to old age [9,
13].
The frequency spread of melanocytic nevi
in the body segments is strictly interdependent
with individual phenotype, with predisposing ge-
netic factors and exposure to harmful factors di-
rected towards the skin, such as exposure to ul-
traviolet radiation, are deemed to have a minor
role [5]. From this perspective, what appear as
benign melanocytic nevi may degenerate and
become malignant [15]. Such changes to the skin
can be demonstrated successfully on experi-
mental animal models [6].