| Material and methods.
Clinical observation of a patient with cardiac
X syndrome, which refers to a particular type of coronary heart disease, is described in detail. Diagnostic criterion of the
disease is the absence of hemodynamic significant stenoses of the coronary arteries against the background of ongoing
signs of myocardial ischemia, with recorded ST-segment depression of more than 1,5 mm and duration of more than
1 minute, established with a 48-hour monitoring of the electrocardiogram.
Results and discussion.
Atypical character
of the pain syndrome was seen in the patient. The use of the late current inhibitor of sodium ions ranolazin has led to
an increase in exercise tolerance by 55% and to a decrease in ischemia duration by 48%. The number of episodes of
depression decreased in 2 times according to the holter ECG monitoring compared to the results of standard therapy.
The ATP-dependent potassium channel activator nicorandil has reduced the duration of ischemia by 11% and the number
of depression episodes — by 16,6% according to holter ECG monitoring.
Conclusion.
Both drugs in combination with
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