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flavonoidy-vostochnoaziatskogo-vida-serratula-manshurica-kitag
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Для цитирования: Мягчилов А.В., Соколова Л.И., Горовой П.Г. Флавоноиды восточноазиатского вида Serratula manshurica Kitag. // Химия растительного сырья. 2021. №1. С. 167–173. DOI: 10.14258/jcprm.2021018269. Myagchilov A.V. 1,2* , Sokolova L.I. 1 , Gorovoy P.G. 2 FLAVONOIDS OF THE EAST ASIAN SPECIES SERRATULA MANSHURICA KITAG. 1 Far Eastern Federal University, o. Russkiy, Ajax, 10, Vladivostok, 690950 (Russia), e-mail: dfdfdf47@yandex.ru 2 G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch RAS, pr.100-Let of Vladivostok, 159, Vladivostok, 690922 (Russia) One of the poorly studied and widespread plants in the Russian Far East is the Manchurian saw-wort ( Serratula mans- hurica Kitag.). It is known that this plant is rich in phytoecdysteroids, which have high biological activity (anabolic, adaptogenic, cardiotropic, immunomodulatory effects). Two biologically active compounds of the flavonoid class were isolated from the aerial part of Serratula manshurica Kitag. Growing in the Primorsky Kray of the Far East of Russia by liquid extraction and recrystal- lization methods: quercetin-4'-O-β-D-glucuronopyranoside and apigenin-7-O-β-D-glucuronopyranoside. The structure of the iso- lated compounds was proved by UV-, NMR-spectroscopy and mass spectrometry with electrospray ionization. The quantitative content of flavonoids in the aerial part of the Serratula manshurica plant in different phenological phases of plant development (luteolin-4'-O-β-D-glucuronopyranoside, quercetin-4'-O-β-D-glucuronopyranoside, apigenin-7-O-β-D-glucuronopyranoside, 3- methylquercetin-4'-O-β-D-glucuronopyranoside, quercetin, apigenin, 3-methylquercetin, luteolin, isokaempferide) was deter- mined by the method of reversed phase liquid chromatography (RP HPLC). It was shown that the maximum content of flavonoid aglycones in plants was observed during the beginning of the growing season and in the budding phase, and their glycosides - during the flowering phase. Thus, to obtain plant material with the maximum content of flavonoid aglycones (quercetin, 3- methylquercetin, luteolin) the collection of vegetative mass should be carried out during the beginning of the growing season, and their glycosides - during the flowering period. Serratula manshurica Kitag., which grows abundantly on the territory of Primorsky Krai, can be considered a constantly renewable and promising source for obtaining flavonoids. Keywords: Serratula manshurica , flavonoids, quercetin-4'-O-β-D-glucuronopyranoside, apigenin-7-O-β-D-glucuronopy- ranoside, 3-methylquercetin-4'-O-β-D-glucuronopyranoside, quercetin, 3-methylquercetin, luteolin, isokaempferide. * Corresponding author. Ф ЛАВОНОИДЫ ВОСТОЧНОАЗИАТСКОГО ВИДА S ERRATULA MANSHURICA K ITAG . 173 жүктеу/скачать 0,63 Mb. Достарыңызбен бөлісу:
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