Объединение юридических лиц в форме ассоциации «общенациональное движение «бобек»



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12:1 МЕДИЦИНСКИЕ НАУКИ

Results and their discussion
– Hematological parameters in diabetes mellitus are 
disturbed very often. Several parameters that are disturbed can be named: WBC, RBC, Hematocrit, 
ESR and so on.
These changes are associated with an increase in both the plasma and whole blood 
viscosity, which determine the blood flow resistance and microcirculation, leading to the 
development of microvascular complications. Moreover, diabetes is also associated with an 
increased risk of atherosclerosis. The above mentioned hemorheological disturbances can amplify 
the hemodynamic disturbances. 
Assessment of one of the main hematological parameters in diabetic mellitus patients is 
WBC. Evaluating the levels of WBC at admission, 24 out of 51 (47.0%) have shown leukocytosis, 
27 out of 51 (52.9%) have normal levels of WBC. Among the 24 patients, 16 were male and 8 
were female. The mean value of WBC at admission among 24 patients is 16.69±0.34 10*9g/L 
(normal range: 4-9 10*9g/L).


INTERNATIONAL SCIENTIFIC JOURNAL 
«GLOBAL SCIENCE AND INNOVATIONS 2023: CENTRAL ASIA» 
ASTANA, KAZAKHSTAN, NOVEMBER 2023 
59 
The highest level of WBC among 24 patients is 26.0 10*9g/L who is clinically diagnosed 
with necrosis of the 2
nd
and 3
rd
fingers of the left foot as a complication of diabetic mellitus. Out 
of 24 patients, 7 (29.1%) patients leucocyte levels have reached the normal level after proceeding 
with treatment. Reassessment of patients with leukocytosis at discharge after proceeding with 
treatment had positive dynamic results with the treatment compared to the levels at admission. 17 
patients have higher than normal level of WBC at discharge but the values are less compared to 
admission. Out of them, 14 were male and 3 were female. The mean value of WBC at discharge 
is 9.25±0.25 10*9g/ L (normal range 4-9 10*9g/L). When comparing the mean values at admission 
and discharge, a dramatic fall in the level can be seen, which is a positive sign of clinical treatment. 
Illustrating the leucocytes separately with regards to neutrophils, lymphocytes and monocytes. All 
24 patients with leukocytosis have neutrophilia, lymphocytopenia and a low or normal range of 
monocytes. The mean value of neutrophilia at admission is 76% (normal range: 45-70%). With 
the administration of medication and surgical treatment, the mean neutrophil level at discharge is 
71.2%. 
Anemia is one of the most common hematological abnormalities that is mostly seen among 
diabetic patients. With regards to the erythrocyte level, during admission, 23 (45.0%) patients had 
a lower level of erythrocyte level, the mean value is 3.39±0.07 10*12/L (normal range: 3.9-5.1 
10*12/L). Out of 23, 14 patients were male and 9 were female. The lowest level of erythrocyte 
was 2.45 10*12/L. Most of the cases with anemic conditions progress to relative increment of the 
erythrocyte count at discharge compared to admission, after treatment. At the time of discharge, 
out of 23, 20 (86.9%) were still in anemic condition with higher erythrocyte count compared to 
admission. The mean value at discharge is 3.76±0.36 10*12/L (normal range 3.9-5.1 10*12/L). 
In respect to the hemoglobin level of these 51 patients, 35 (68.6%) were diagnosed with 
low hemoglobin (normal range: 130-170g/l). Anemic conditions are categorized into 3 subtypes 
according to the level of hemoglobin concentration.
Mild anemic patients are 24 (68.5%) with higher than 100g/l. 9 (25.7%) were diagnosed 
with moderate anemia in the range of 80-100g/L and 2 (5.7%) were diagnosed with severe anemia 
in the range less than 80g/l. out of 24 mild anemic patients, 17 patients were still mild anemic at 
discharge. 6 were progressed to moderate anemic stage and 1 patient has reached to normal 
hemoglobin level at discharge. Out of 9 patients who were diagnosed as moderate anemic at 
admission, 5 patients had persistent level of moderate anemia and 4 patients were able to increase 
the level of hemoglobin up to mild anemic stage at discharge. 2 patients who were diagnosed as 
severe anemic at admission were upgraded to moderate anemic stage with clinical therapy at 
discharge. 
Erythrocyte sedimentation rate is investigated in 33 patients at admission. All these patients 
had elevated levels of ESR (normal range:2-10mm/hr). 39.3% have increased the ESR up to 50 
mm/hr and 60.6% have ESR higher than 50 mm/hr at admission. 17 patients have been investigated 
for ESR at discharge. 47.0% have increased the ESR up to 50 mm/hr and 52.9% have ESR higher 
than 50 mm/hr at discharge. The mean values at both admission and discharge are 51.9±2.11 
mm/hr and 35.0±1.12 mm/hr (normal range: 2-10 mm/hr) respectively. When comparing the mean 
values, the majority of the patients have decreased their ESR compared to their admission values, 
which is a positive dynamic effect. 
Concerning the thrombocyte levels of 51 patients, 6 (11.7%) were admitted with 
thrombocytosis, 40 have normal levels of thrombocytes, and 5 were not investigated for their level 
of thrombocytes. These above mentioned 6 patients had persistently high levels of thrombocytes 
even during discharge, but their values are low compared to admission. The mean values of 
thrombocytosis at admission and discharge are 545±44.7 10*9/L and 523±22.6 10*9/L 
respectively (normal range 150-450 10*9/L). 



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