INTERNATIONAL SCIENTIFIC JOURNAL «GLOBAL SCIENCE AND INNOVATIONS 2023: CENTRAL ASIA» ASTANA, KAZAKHSTAN, NOVEMBER 2023 58 HEMATOLOGICAL CHANGES IN DIABETIC MELLITUS PATIENTS ON THE STAGES OF SURGICAL TREATMENT Warnakulasuriya F.R.S, Obuxovich A.R. Student of Grodno State Medical University, Assistant lecturer
Scientific Supervisor- Assoc.Prof. Vasilevsky Vladmir Petrovich
Grodno, Belarus
Background- Diabetes mellitus (DM) is a disease of inadequate control of blood glucose ranges [1]. Patients with poorly controlled blood glucose levels show alterations in metabolic, cellular and immunological pathways, resulting in significant changes to hemorheological parameters [2]. Hematological changes include the change in function, structure, and metabolism of White blood cells (WBC), Red blood Cells (RBC), platelet count, and platelet indices. Hematological parameters are not precisely involved in the diagnose of diabetic mellitus but these parameters should still be regularly tested for early diagnosis and proper management of diabetes-related complications [2]. WBC has the most significant role in the prediction of diabetic mellitus type 2 [3]. Several key hematological parameters, such as white blood cell count, red blood cell, hemoglobin(Hb), hematocrit, Erythrocyte Sedimentation Rate (ESR) are investigated and evaluated in this context. Purpose- The evaluation of practical importance of the hematological abnormalities and dynamics in patients with Diabetes mellitus at the stages of surgical treatment. Key words- Diabetic Mellitus, Hematological abnormalities The materials of research - The analysis of the results of 51 patients who were hospitalized
over the past 10 months (2023.01-2023.10) in the purulent department of the University clinic of
Grodno State Medical University in Grodno, Belarus with diagnosis of Diabetic Mellitus. For
statistical data processing, the Pearson's χ2 test was used. The p < 0.05 level was accepted as
statistically significant. Among the 51 patients there were 33 (64,7%) men and 18 (35.2%) women
aged from 49 to 86 years. The majority of patients are under the category of 61-65 age group. The
second highest patients are under the age group of 71-75. Different surgical treatment
methodologies have been applied among these patients. 10% have undergone amputation of lower
extremity at lower third of thigh, 20% have performed angioplasty of lower extremity arteries
including femoral popliteal shunting and 13.3%, drainage of phlegmon. Amputation of toes have
been done on 21.6%. Necrectomy was performed in 5%. Local wound debridement was performed
on 26.6%.