«Фараби Әлемі» атты студенттер мен жас ғалымдардың халықаралық конференциясы
176
INVESTIGATION OF THE PROPERTIES OF COMPOSITIONS BASED ON
POLYVINYL ALCOHOL AND GELATIN
Yessenov A.A., Otegenova B.O.
Scientific supervisor: PhD Kudaibergenova B.M.
Al-Farabi Kazakh National University
almas01ktl@gmail.com
In recent years, the search for polymer carriers of drug to obtain effective composite drugs
forms with prolonged action has attracted increasing interest and is aimed at creating materials with
unique properties through the use of original and simple production methods.
In
this work, we studied the possibility of obtaining composite materials on the basis of
natural polymers – polyvinyl alcohol (PVA) and gelatin with the addition
of biologically active
complex - alchidine, for further use as carriers of medicinal substances. The choice of PVA is also
due to a number of valuable properties: high swelling capacity, indifference to other raw materials,
non-toxicity, sorption capacity, and availability. For this purpose, different concentrations of the gel
were obtained, such as 10 %, 13 %, 15 %.
In this regard, the possibility of obtaining gels of PVA and its compositions with gelatin was
studied in the work.
Composite gels were obtained and the morphological structure of the gels and the influence of
various factors on the swelling properties of the gels were studied.
The properties of composite materials will largely depend on its constituent components. In
this regard, the viscosity, density and melting point of the obtained gels were studied. As a result of
the conducted swelling studies, it was revealed that the values of the swelling ability of composite
gels are significantly lower compared to the degrees of swelling of conventional PVA gels. With
increasing of the content of gelatin
in the composite system, decreasing of swelling degree is
observed.
The homogeneity of the resulting compositions is also observed by the method of rotational
viscosity.
Thus, as a result of the conducted studies, it was found that the nature of the interaction of
gelatin with PVA depends on the concentration of the polymer. A promising possibility of using
gelatin and PVA to create compositions with good stability
and mutual compatibility is
investigated. We suppose that the obtained results improve the possibility of using our compositions
in medical purposes.
«Фараби Әлемі» атты студенттер мен жас ғалымдардың халықаралық конференциясы
177
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